Body-on-a-Chip have emerged as a promising drug screening technologies. We fabricated a new microfluidic device for Body-on-a-Chip, integrating pneumatic micropump for a medium circulation loop, via original grayscale lithography. We further applied this device to study anti-cancer drug response on human heart and liver cancer cells.
[Applications]
- in vitro systems for drug development
- Personalized medicine
[Publication]
- Kato et al., Development of a Body-on-a-Chip Using 3-D Microstructuring Technique, IEEJ Trans. SM, Vol.136-E, No.6, 2016, pp.229-236.